Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia-reperfusion injury and its mechanism of UTR-RhoA-ROCK pathway inhibition.

Xiao-Qing SunShuo ChenLiang-Fang WangZhi-Wu Chen

Published in: The Journal of pharmacy and pharmacology (2018)

Total flavones of Rhododendron simsii Planch flower had a protective effect on ischaemia-reperfusion injury in isolated rat heart, which may be attributed to the blocking of UTR and subsequent inhibition of the RhoA-ROCK pathway.

Keyphrases

cerebral ischemia
acute myocardial infarction
heart failure
oxidative stress
acute ischemic stroke
atrial fibrillation
subarachnoid hemorrhage
brain injury
percutaneous coronary intervention
coronary artery disease
acute coronary syndrome