Intermolecular fluoroamination of allenes towards substituted vinyl fluorides.
Vibha TiwariJacob T BinghamShubham VyasAnand SinghPublished in: Organic & biomolecular chemistry (2020)
A synthetic method towards fluorinated allylamines using allene precursors is reported. A variety of heterocyclic amines were employed as nucleophiles in a Selectfluor promoted intermolecular fluoroamination reaction. This strategy provides a novel synthetic route to access vinyl fluorides with a vicinal amine moiety.
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