Soluble epoxide hydrolase inhibitor promotes immunomodulation to inhibit bone resorption.

Marcelo Henrique NapimogaE P RochaC A Trindade-da-SilvaA P D DemasiE F MartinezC G MacedoH B AbdallaA BettaiebF G HajJ T Clemente-NapimogaB InceogluB D Hammock

Published in: Journal of periodontal research (2018)

The sEH inhibitor, TPPU, showed immunomodulatory effects, decreasing bone resorption and inflammatory responses in a bone resorption mouse model.

Keyphrases

bone loss
bone mineral density
mouse model
soft tissue
bone regeneration
postmenopausal women
body composition