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Long-lasting mechanical hypersensitivity and CRF receptor type-1 neuron activation in the BNST following adolescent ethanol exposure.

Natalia B BertagnaLisa WilsonConnor K BaileyFábio Cardoso CruzLucas Albrechet-SouzaTiffany A Wills
Published in: Alcohol, clinical & experimental research (2023)
Our results support the conclusion that intermittent ethanol exposure can induce mechanical hypersensitivity, potentially through the activation of BNST CRFR1 neurons. These findings provide a basis for future studies aimed at evaluating specific subpopulations of BNST neurons and their contribution to pain in individuals with a history of alcohol use.
Keyphrases
  • spinal cord
  • chronic pain
  • drug induced
  • young adults
  • mental health
  • pain management
  • neuropathic pain
  • childhood cancer