Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene.
Helena Palma-GudielElisenda EixarchFátima CrispiSebastián MoránAnthony S ZannasLourdes FañanásPublished in: Clinical epigenetics (2019)
Prenatal adverse environment during the third trimester of pregnancy is associated with both (i) developmental immaturity in terms of epigenetic age, and (ii) decreased CpG-specific methylation in a gene involved in hypoxia response and schizophrenia genetic liability.