Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy for Cardiovascular Disease Prevention.
Michel KiflenAnn LeShihong MaoRicky LaliSukrit NarulaFeng XieGuillaume ParéPublished in: Circulation. Genomic and precision medicine (2022)
This study suggests that using PRS alongside existing guidelines might be cost-effective for CVD. Stronger predictiveness combined with decreased cost of PRS could further improve cost-effectiveness, providing an economic basis for its inclusion into clinical care.