Supramolecular helix of an oligomeric azapeptide building block containing four β-turn structures.

Oligomers of benzoylalanine-based amidothioureas containing four β-turn structures spaced by meta -substituted benzenes were shown to undergo assembly in dilute CH 3 CN solution into supramolecular helices of enhanced supramolecular helicity, whereas those spaced by para -substituted benzene spacer(s) or those spaced by meta -substituted benzenes but with one or two β-turns exhibit a substantially decreased tendency of assembling.