Inactivation of SARS-CoV-2 infectivity in platelet concentrates or plasma following treatment with ultraviolet C light or with methylene blue combined with visible light.

Jody Hobson-PetersAlberto A AmarillaLina Rustanti Denese C Marks Eileen V RoulisAlexander A KhromykhNaphak ModhiranDaniel WattersonStefan ReichenbergFrank TolksdorfChryslain SumianAxel Seltsam Ute Gravemann Helen M Faddy

Published in: Transfusion (2023)

SARS-CoV-2 infectivity was reduced in plasma and platelets following treatment with the THERAFLEX MB-Plasma and THERAFLEX UV-Platelets systems, to the limit of detection, respectively. These PI technologies could therefore be an effective option to reduce the risk of transfusion-transmitted emerging pathogens.

Keyphrases

sars cov
visible light
respiratory syndrome coronavirus
cardiac surgery
red blood cell
coronavirus disease
gram negative
loop mediated isothermal amplification
light emitting