Outcomes and predictors of left ventricle recovery in patients with severe left ventricular dysfunction undergoing transcatheter aortic valve implantation.
Guy WitbergAmos LeviYeela Talmor-BarkanMarco BarbantiRoberto ValvoGiuliano CostaValentina FrittittaOle de BackerYannick WillemenMark van Der DorpelMatias MonAtsushi SugiuraMitsumasa SudoGiulia MasieroEdoardo PancaldiDabit ArzamendiSandra Santos-MartinezJose A BazKlemen SteblovnikVictor MauriMatti AdamHendrik WienemannDavid ZahlerManuel HeinPhilipp RuileBrídóg Nic AodhaCarmelo GrassoLuca BrancaRodrigo Estévez-LoureiroIgnacio J Amat-SantosDarren MylotteMatjaz BuncGiuseppe TarantiniLuis Nombela-FrancoLars SondergaardNicolas M Van MieghemAriel FinkelsteinRan KornowskiPublished in: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (2024)
LV recovery following TAVI and the extent of this recovery are major determinants of midterm mortality in patients with severe AS and severe LV dysfunction undergoing TAVI. Patients with no previous MI and those with an mAVG >40 mmHg show the best results following TAVI, which are at least equivalent to those for patients without severe LV dysfunction. (ClinicalTrials.gov: NCT04031274).
Keyphrases
- transcatheter aortic valve implantation
- aortic stenosis
- aortic valve
- ejection fraction
- aortic valve replacement
- transcatheter aortic valve replacement
- left ventricular
- early onset
- oxidative stress
- end stage renal disease
- heart failure
- peritoneal dialysis
- mitral valve
- newly diagnosed
- acute myocardial infarction
- coronary artery disease
- type diabetes
- metabolic syndrome
- risk factors
- hypertrophic cardiomyopathy
- adipose tissue
- patient reported outcomes
- insulin resistance