Lifetime body mass index and grip strength at age 46 years: the 1970 British Cohort Study.

Rachel Cooper David J Tomlinson Mark Hamer Snehal M Pinto Pereira

Published in: Journal of cachexia, sarcopenia and muscle (2022)

Higher BMI from childhood onwards is associated with stronger grip at age 46 years. This suggests that, at this age, anabolic effects of fat on muscle are outweighing the catabolic effects thought to lead to the manifestation of sarcopenic obesity later in life, especially among men. Midlife may be an optimal time to intervene to prevent sarcopenic obesity.

Keyphrases

insulin resistance
metabolic syndrome
weight gain
weight loss
type diabetes
adipose tissue
skeletal muscle
high fat diet induced
body mass index
physical activity
middle aged
early life