Transitions in depression: if, how, and when depressive symptoms return during and after discontinuing antidepressants.

Arnout C Smit Evelien Snippe Laura F Bringmann H J Rogier Hoenders Marieke Wichers

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2022)

Meaningful change is common in patients discontinuing antidepressants, and there is substantial heterogeneity in how and when these changes occur. Depressive symptom change at the macro-level is not the same as depressive symptom change at the micro-level.

Keyphrases

depressive symptoms
end stage renal disease
major depressive disorder
bipolar disorder
ejection fraction
chronic kidney disease
patient reported
stress induced
prognostic factors
peritoneal dialysis
sleep quality
single cell
physical activity