Arteriovenous Fistula-induced Cardiac Remodeling Shows Cardioprotective Features in Mice.

Shin-Rong LeeStephanie ThornNicole GuerreraLuis GonzalezRyosuke TaniguchiJohn LangfordAlbert J SinusasAlan Dardik

Published in: JVS-vascular science (2021)

AVF stimulate adaptive cardiac hypertrophy in wild-type mice without heart failure or pathological fibrosis. Transcriptional correlates suggest AVF-induced cardiac remodeling has some cardioprotective, although also arrhythmogenic features.

Keyphrases

wild type
heart failure
left ventricular
high glucose
diabetic rats
high fat diet induced
drug induced
transcription factor
oxidative stress
atrial fibrillation
type diabetes
adipose tissue
insulin resistance
acute heart failure
stress induced