The genomic diversification of grapevine clones.

Amanda M VondrasAndrea MinioBarbara Blanco-UlateRosa Figueroa-BalderasMichael A PennYongfeng ZhouDanelle SeymourZirou YeDingren LiangLucero K EspinozaMichael M AndersonM Andrew WalkerBrandon GautDario Cantu

Published in: BMC genomics (2019)

These data support three major conclusions. First, repetitive intergenic space is a major driver of clone genome diversification. Second, clones accumulate putatively deleterious mutations. Third, the data suggest selection against deleterious variants in coding regions or some mechanism by which mutations are less frequent in coding than noncoding regions of the genome.

Keyphrases

electronic health record
copy number
big data
genome wide
high frequency
data analysis
gene expression
machine learning