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Cardiac transplantation in adults with congenital heart disease: A single center case series.

Christopher A HeidRaghav ChandraCharles LiuJessica PruszynskiMitri K KhouryRyan VelaXue ZengKayla MaaraouiAnya KalsbeekW Steves RingAlpesh A AminJohn MuralaMatthias Peltz
Published in: Clinical transplantation (2021)
Modern advances in palliation of congenital heart defects (CHD) has led to increased survival into adulthood. Many of these patients require heart transplantation as adults. There are limited data on adult CHD transplantation. Historically, these patients have had worse perioperative outcomes with improved long-term survival. We retrospectively analyzed 262 heart transplants at a single center, 18 of which were for adult CHD. Here, we report our series of 18 CHD recipients. We detail the palliative history of all CHD patients and highlight the added technical challenges for each of the 18 patients at transplant. In our analysis, CHD patients had more prior cardiovascular surgeries as well as longer transplant operative and bypass times. Despite this, there were no differences in perioperative and long-term outcomes. We have added patient and institution specific data for transplanting patients with adult CHD. We hope that our experience will add to the growing body of literature on adult CHD transplantation.
Keyphrases
  • ejection fraction
  • newly diagnosed
  • systematic review
  • heart failure
  • type diabetes
  • case report
  • left ventricular
  • young adults
  • depressive symptoms
  • big data
  • insulin resistance
  • data analysis
  • cell therapy