Race-Associated Genomic Correlates of Therapeutic Response in African American Patients With Non-Small-Cell Lung Cancer.
Pin LiKaitlyn L O'SheaFrank M WolfAnna B BerryShirish M GadgeelAmanda PillingPublished in: JCO precision oncology (2023)
In a real-world cohort of patients with NSCLC, we identified race-associated differences in therapeutic outcomes and described molecular characteristics in NHB and NHW patients with NSCLC. To proactively identify patients most likely to respond to systemic therapies, a more comprehensive approach is needed to help guide therapy selection in individualized patient populations.
Keyphrases
- african american
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- advanced non small cell lung cancer
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- type diabetes
- case report
- brain metastases
- stem cells
- bone marrow
- adipose tissue
- patient reported outcomes
- copy number
- dna methylation
- smoking cessation
- weight loss
- glycemic control
- replacement therapy