A Cohort Study of CNS Tumors in Multiple Endocrine Neoplasia Type 1.

Thomas Graillon Pauline Romanet Clara Camilla Camille Gelin Romain Appay Catherine Roche Arnaud Lagarde Gregory Mougel Kaissar Farah Maelle Le Bras Julien Engelhardt Michel Kalamarides Matthieu Peyre Aymeric Amelot Evelyne Emery Elsa Magro Hélène Cebula Rabih Aboukais Catherine Bauters Emmanuel Jouanneau Moncef Berhouma Thomas Cuny Henry Dufour Hugues Loiseau Dominique Figarella Branger Luc Bauchet Christine Binquet Anne Barlier Pierre Goudet

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

The incidence of each CNS tumor was higher in the MEN1 population than in the French general population. Meningiomas and ependymomas should be considered part of the MEN1 syndrome, but somatic molecular data are missing to conclude for astrocytomas and schwannomas.

Keyphrases

blood brain barrier
middle aged
risk factors
electronic health record
big data
case report
copy number
gene expression
machine learning
dna methylation
data analysis