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The clinically used PARP inhibitor olaparib improves organ function, suppresses inflammatory responses and accelerates wound healing in a murine model of third-degree burn injury.

Akbar AhmadGabor OlahDavid N HerndonCsaba Szabó
Published in: British journal of pharmacology (2017)
This article is part of a themed section on Inventing New Therapies Without Reinventing the Wheel: The Power of Drug Repurposing. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.2/issuetoc.
Keyphrases
  • wound healing
  • dna damage
  • signaling pathway
  • dna repair
  • benign prostatic hyperplasia
  • lower urinary tract symptoms
  • emergency department
  • drug induced