COQ2 and SNCA polymorphisms interact with environmental factors to modulate the risk of multiple system atrophy and subtype disposition.
Ming-Che KuoYing-Che LuChun-Hwei TaiBing-Wen SoongFu-Chang HuMeng-Ling ChenChin-Hsien LinRuey-Meei WuPublished in: European journal of neurology (2022)
Certain COQ2 and SNCA SNPs interact with common environmental factors to modulate MSA etiology and subtype disposition. The mechanisms underlying the observed correlation between G-E interactions and MSA etiopathogenesis warrant further investigation.
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