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The Effect of Mesenchymal Stem Cell-Enriched Scaffolds on MMP-8 and TGF-β Levels of Vertebrae Postlaminoplasty in Rabbit Model.

Ahmad Jabir RahyussalimRoni Eka Sahputranull YanwirastiMenkher ManjasYudan WhulanzaTri KurniawatiDina AprilyaMuhammad Luqman Labib Zufar
Published in: Stem cells and cloning : advances and applications (2021)
The significant decrease in MMP-8 levels, increase in TGF-β levels, and increased number of osteoblasts on MSC-seeded polylactic acid scaffolds could be useful to support the laminoplasty procedure to prevent restenosis because it was biocompatible and promoted the bone healing process.
Keyphrases
  • mesenchymal stem cells
  • transforming growth factor
  • bone marrow
  • minimally invasive
  • bone mineral density
  • ionic liquid
  • signaling pathway
  • drug release