The Use of Middle Latency Auditory Evoked Potentials (MLAEP) as Methodology for Evaluating Sedation Level in Propofol-Drug Induced Sleep Endoscopy (DISE) Procedure.
Michele AriglianiDomenico M ToraldoEnrico CiavolinoCaterina LattanteLuana ConteSerena ArimaCaterina AriglianiAntonio PalumboMichele De BenedettoPublished in: International journal of environmental research and public health (2021)
To analyze the middle latency auditory evoked potential index (MLAEPi), compared to the standard bispectral index (BIS), as a method for evaluating the sedation level in drug-induced sleep endoscopy (DISE). In this controlled clinical study on a sample of 99 obstructive sleep apnea (OSA) or snoring patients, we compared the MLAEPi with the BIS after propofol infusion during the standard DISE technique in order to define the MLAEPi values within the observational window of the procedure. The DISE procedure was divided into eight steps, and we collected both MLAEPi and BIS data values from the same patient in every step. The MLAEPi showed a faster response than the BIS after propofol infusion during DISE. Therefore, the clinical use of the MLAEPi in evaluating the sedation level seems to be a good alternative to the current technological standards.
Keyphrases
- drug induced
- liver injury
- obstructive sleep apnea
- ionic liquid
- end stage renal disease
- minimally invasive
- mechanical ventilation
- ejection fraction
- low dose
- adverse drug
- newly diagnosed
- physical activity
- working memory
- chronic kidney disease
- sleep quality
- small bowel
- intensive care unit
- peritoneal dialysis
- prognostic factors
- hearing loss
- risk assessment
- patient reported outcomes
- electronic health record
- deep learning
- extracorporeal membrane oxygenation