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Beyond "living fossils": Can comparative genomics finally reveal novelty?

Gustavo SanchezOleg SimakovDaniel S Rokhsar
Published in: Molecular ecology resources (2021)
Cephalopods have recently moved into the research focus due to the growing number of sequenced genomes, molecular tools, and laboratory culture (Albertin & Simakov, 2020)⁠. Genome data now allows us to ask how the many known novelties of cephalopod morphology are reflected in their genomes and gene regulation. A crucial gap in this understanding has been the limited information for the Nautilus, the last survivor of a cephalopod lineage that diverged from the highly derived coleoid clade (octopus, squid, cuttlefish) around 400 million years ago. The publication of Nautilus genomes (in this issue of Molecular Ecology [Huang et al., 2021; Zhang et al., 2021])⁠ will help us understand which genetic changes happened when, and ultimately how they contributed to cephalopod evolution.
Keyphrases
  • genome wide
  • single cell
  • electronic health record
  • single molecule
  • big data
  • dna methylation
  • health information
  • gene expression
  • healthcare
  • copy number
  • deep learning
  • social media
  • artificial intelligence