HER2-low breast cancer could be associated with an increased risk of brain metastasis.
Deniz Can GuvenMehmet Burak KayaBurak FedaiMucahit OzdenHasan Cagri YildirimKemal KosemehmetogluNeyran KertmenOmer DizdarAysegul UnerSercan AksoyPublished in: International journal of clinical oncology (2021)
In this study, we observed an increased risk of brain metastasis in localized breast cancer patients with HER2-low disease. We think that a high level of vigilance and a low threshold for brain imaging could benefit HER2-low breast cancer patients similar to the patients with HER-positive disease.