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Trastuzumab-induced toxic epidermal necrolysis in a Her-2-positive metastatic breast cancer patient-A rare case report.

Jannatul FerdauseSura Jukrup MomtahenaRubama KarimAditi Paul ChowdhuryNowshin Taslima HossainMd Ariful IslamMaruf Bin HabibA K M Shafiul KadirMd Ariful Haque
Published in: Clinical case reports (2024)
Toxic Epidermal Necrolysis (TEN) is a rare, but potentially fatal mucocutaneous reaction, that may occur due to an immunologic response to certain medications. However, TEN triggered by Trastuzumab is extremely rare. Early diagnosis, recognition, and prompt cessation of the offending drugs and initiation of steroid therapy with supportive management are the most important actions for managing TEN. Although rare, it is important to be vigilant about this potential adverse reactions associated with trastuzumab to ensure patient safety and contribute to better outcomes.
Keyphrases
  • metastatic breast cancer
  • patient safety
  • case report
  • epidermal growth factor receptor
  • quality improvement
  • emergency department
  • risk assessment
  • adipose tissue
  • oxidative stress
  • tyrosine kinase
  • cell therapy