The Usefulness of Genotyping of Celiac Disease-Specific HLA among Children with Type 1 Diabetes in Various Clinical Situations.
Grazyna DejaDominika SikoraAleksandra Pyziak-SkupieńKarolina KlenczarRafał DejaPrzemysława Jarosz-ChobotPublished in: Journal of diabetes research (2020)
Genotyping HLA DQ2/DQ8 as a negative screening has limited use in assessing the risk of CD at the diabetes onset and does not allow to verify the diagnosis of CD in doubtful situations. The presence of the DRB1∗04 allele modulates the risk of CD and significantly reduces it and can predict a potential form.