Comprehensive two-dimensional ion chromatography (2D-IC) coupled to a post-column photochemical fluorescence detection system for determination of neonicotinoids (imidacloprid and clothianidin) in food samples.
Nadeem MuhammadFenglian WangQamar SubhaniQiming ZhaoMuhammad Abdul QadirHairong CuiYan ZhuPublished in: RSC advances (2018)
There are increasing concerns about the dietary risks of neonicotinoids (NNIs); therefore their sensitive and accurate determination in dietary products is indispensable. However, the complex composition of agricultural food matrixes makes their extraction and quantitative determination a challenging task. Realizing this need, we herein report a simple, cost-effective, selective and sensitive fluorescence analytical workflow for analyses of two non-fluorescent neonicotinoids imidacloprid (IMI) and clothianidin (CLT) in six complex food samples (honey, ginger, durian, apple, tomato, cucumber) by online clean-up of sample extracts using two-dimensional ion chromatography (2D-IC) and a subsequent online post column UV induced fluorescence detection system. This online clean-up setup has proven advantageous to improve the limit of detection, potentially diminish matrix effects, and reduce analysis time and labor. The developed method showed excellent analytical figures of merit including linearity, selectivity, repeatability, recovery, and resolution for analysis of IMI and CLT in food samples.
Keyphrases
- liquid chromatography
- solid phase extraction
- human health
- mass spectrometry
- single molecule
- high performance liquid chromatography
- tandem mass spectrometry
- label free
- loop mediated isothermal amplification
- health information
- risk assessment
- molecularly imprinted
- real time pcr
- high speed
- high resolution
- climate change
- energy transfer
- simultaneous determination
- oxidative stress
- quantum dots
- living cells
- high glucose
- electronic health record
- endothelial cells
- fluorescent probe