Blood Neurofilament Light Chain in Genetic Ataxia: A Meta-Analysis.

Linliu PengShang WangZhao ChenYun PengChunrong WangZhe LongHuirong PengYuting ShiXuan HouLijing LeiLinlin WanMingjie LiuGuangdong ZouLu ShenKun XiaRong QiuBei-Sha Tang Tetsuo AshizawaThomas KlockgetherJiang Hong

Published in: Movement disorders : official journal of the Movement Disorder Society (2021)

bNfL can be used as a potential biomarker to predict disease onset, severity, and progression of genetic ataxia. Reference-value setting of bNfL should be divided according to age. © 2021 International Parkinson and Movement Disorder Society.

Keyphrases

genome wide
early onset
copy number
cerebrospinal fluid
dna methylation
gene expression