Possible Prophylactic Effects of Sulforaphane on LPS-Induced Recognition Memory Impairment Mediated by Regulating Oxidative Stress and Neuroinflammatory Proteins in the Prefrontal Cortex Region of the Brain.
Noor Ahmed AlzahraniKhulud Abdullah BahaidrahRasha A MansouriRahaf Saeed AldhahriGamal S Abd El-AzizBadrah S AlghamdiPublished in: Biomedicines (2024)
The obtained results suggested that SFN has a potential protective property to mitigate the behavioral and biochemical impairments induced by chronic LPS administration and suggested to be via an AMPK/caspase-3-dependent manner.
Keyphrases
- lps induced
- prefrontal cortex
- inflammatory response
- oxidative stress
- induced apoptosis
- cell death
- white matter
- resting state
- working memory
- skeletal muscle
- dna damage
- ischemia reperfusion injury
- diabetic rats
- anti inflammatory
- cerebral ischemia
- human health
- multiple sclerosis
- blood brain barrier
- protein kinase
- heat shock