Enantioselective Copper-Catalyzed Hydroamination of Vinylarenes with Anthranils.
Fang XieBingxue ShenXingwei LiPublished in: Organic letters (2018)
Copper hydride-catalyzed asymmetric hydroamination of olefins with anthranils has been realized in high efficiency and high enantioselectivity, affording enantioenriched secondary arylamines tethered to a benzylic alcohol. The bifunctionality of the product has been employed in diverse derivatization reactions.
Keyphrases
- high efficiency
- ms ms
- liquid chromatography tandem mass spectrometry
- high performance liquid chromatography
- room temperature
- gas chromatography mass spectrometry
- simultaneous determination
- liquid chromatography
- alcohol consumption
- tandem mass spectrometry
- gas chromatography
- solid phase extraction
- high resolution