Mycosis fungoides with spongiosis: A potential diagnostic pitfall.

Huma ShamimEmma F JohnsonLawrence E GibsonNneka I Comfere
Published in: Journal of cutaneous pathology (2019)
These cases highlight prominent spongiosis in MF and overlap with common benign inflammatory dermatoses. We present these cases to show the diagnostic pitfalls associated with spongiotic presentations of MF. Dermatitis, psoriasis, and other inflammatory skin conditions not responsive to standard therapy warrant further work-up including biopsy to rule out MF. Multiple skin biopsies and review by a dermatopathologist with expertise in the diagnosis of cutaneous lymphoma is highly recommended.