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Epothilone D accelerates disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Jayden ClarkC A BlizzardM C BreslinE J YeamanK M LeeJ A ChuckowreeT C Dickson
Published in: Neuropathology and applied neurobiology (2018)
The results suggest that EpoD accelerates disease progression in the SOD1G93A mouse model of ALS, and highlights that the pathophysiological involvement of microtubules in ALS is an evolving and underappreciated phenomenon.
Keyphrases
  • amyotrophic lateral sclerosis
  • mouse model