Genetic Variants in the 9p21.3 Locus Associated with Glioma Risk in Children, Adolescents, and Young Adults: A Case-Control Study.

Anna M DahlinCarl WibomUlrika AnderssonDavid M HougaardJonas Bybjerg-GrauholmIsabelle DeltourChristina M HultmanAnna K KählerRobert Karlsson Ulf HjalmarsBeatrice Melin

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)

Our findings line up with existing evidence that some, although not all, established adult glioma risk variants are associated with risk of glioma in children and AYA. Validation of results from genome-wide analyses may reveal novel susceptibility loci for glioma in children and AYA.

Keyphrases

genome wide
young adults
dna methylation
copy number
gene expression
single cell