Prevalence of karyotype alterations in couples with recurrent pregnancy loss in a tertiary center in Brazil.

Elaine Cristina Fontes de Oliveira Ines Katerina Damasceno Cavallo Cruzeiro Cezar Antônio Abreu de Souza Fernando Marcos Reis

Published in: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2024)

The prevalence of parental chromosomal alterations in our study was higher than in most series described in the literature and was associated with increased maternal age. These findings suggest that karyotyping should be part of the investigation for Brazilian couples with RPL, as identifying the genetic etiology may have implications for subsequent pregnancies.

Keyphrases

pregnancy outcomes
risk factors
preterm birth
systematic review
copy number
pregnant women
genome wide