CNS therapeutics: Immune cells break the barriers.

Published in: Science translational medicine (2023)

Peripheral immune cells can be seen as attractive vectors and drug carriers for central nervous system therapeutics because these cells have unique properties that allow them to migrate across the blood-brain barrier, enabling drug delivery to brain regions that are inaccessible to free drugs.

Keyphrases

drug delivery
induced apoptosis
small molecule
cell cycle arrest
blood brain barrier
resting state
white matter
endoplasmic reticulum stress
drug induced
cancer therapy
cerebrospinal fluid
cell death
functional connectivity
pi k akt