Solitary pleural fibroma causing IGF-2-mediated hypoglycaemia in a non-diabetic patient.
Emily LachmannBenjamin BennettRozana RamliSonal SharmaPublished in: BMJ case reports (2024)
A patient without a diagnosis of diabetes mellitus presented to the hospital due to a fall and hypoglycaemia on admission. The patient was found to have recurrent nocturnal fasting hypoglycaemia. CT revealed a large lung mass consistent with a solitary pleural fibroma, a rare tumour associated with insulin-like growth factor 2 (IGF-2) production. This case is an important reminder that potential causes of hypoglycaemia should be considered in non-diabetic patients.
Keyphrases
- type diabetes
- case report
- emergency department
- computed tomography
- blood pressure
- obstructive sleep apnea
- pi k akt
- growth hormone
- magnetic resonance imaging
- adipose tissue
- binding protein
- magnetic resonance
- cell proliferation
- risk assessment
- metabolic syndrome
- image quality
- skeletal muscle
- contrast enhanced
- signaling pathway
- climate change
- rare case
- sleep quality
- wound healing