Multi-Center Assessment of Lymph-Node Density and Nodal-Stage to Predict Disease-Specific Survival in Patients with Bladder Cancer Treated by Radical Cystectomy.
Erik J van GennepFrancesco ClapsPeter J BostromShahrokh F ShariatYann NeuzilletAlexandre R ZlottaCarlo TrombettaMarkus EcksteinLaura S MertensRossana BussaniMaximilian BurgerJoost L BoormansBernd WullichArndt HartmannRoman MayrNicola PavanRiccardo BartolettiM Carmen MirDamien PouesselJohn van der HoevenTheo H van der KwastYves AlloryTahlita C M ZuiverloonYair LotanBas W G van RhijnPublished in: Bladder cancer (Amsterdam, Netherlands) (2024)
LN-density ≥ 20% was an independent predictor of worse DSS in BC patients with LN-involvement at RC. The integration of LN-density and other LN-parameters rather than only conventional pN-stage may contribute to a more refined risk-stratification in BC patients with nodal involvement.