A unimolecular theranostic system with H 2 O 2 -specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells.

A theranostic drug delivery system composed of tetraphenyl-ethene (AIEgen), benzyl boronic ester (trigger), and doxorubicin (drug) was designed and synthesized; its utilities for cell imaging, drug delivery tracking, and cancer cell cytociding were evaluated.