LIPCAR levels in plasma-derived extracellular vesicles is associated with left ventricle remodeling post-myocardial infarction.

Annie TurkiehOlivia BesemeOuriel SauraHenri CharrierJean-Baptiste MichelPhilippe AmouyelThomas ThumChristophe BautersFlorence Pinet

Published in: Journal of translational medicine (2024)

Our data showed that large EVs are the main extracellular vesicle transporter of LIPCAR from heart into the circulation independently of the status, non-failing or HF, in patients. The levels of LIPCAR in EVs isolated from plasma could be used as biomarkers of LVR in post-MI patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
heart failure
prognostic factors
peritoneal dialysis
deep learning
patient reported
pulmonary arterial hypertension
congenital heart disease