Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas.

Qi ZhangYu LouJiaqi YangJunli WangJie FengYali ZhaoLin WangXing HuangQihan FuMao YeXiaozhen ZhangYiwen ChenCe MaHongbin GeJianing WangJiangchao WuTao WeiQi ChenJunqing WuChengxuan YuYanyu XiaoXinhua FengGuoji GuoTingbo LiangXue-Li Bai

Published in: Gut (2019)

There is comprehensive intratumoral and intertumoral heterogeneity in all dimensions of HCC. Based on the results, we propose a novel immunophenotypic classification of HCCs that facilitates prognostic prediction and may support decision making with regard to the choice of therapy.

Keyphrases

decision making
deep learning
machine learning
single cell
high grade
mesenchymal stem cells
cell therapy