Radiation-associated peritoneal angiosarcoma.
Chin Jin SeoSze Min LekGrace Hwei Ching TanMelissa Ching Ching TeoPublished in: BMJ case reports (2017)
Angiosarcomas account for only 1-2% of all soft tissue sarcomas, with the most common site of origin being in the head and neck region. Peritoneal angiosarcoma is an extremely rare tumour and few cases have been reported previously. Presentation of peritoneal angiosarcoma can be very variable, hence making diagnosis difficult. Herein, we review the current literature and describe a rare case of a patient who presented with haemorrhagic ascites, 17 years after radiotherapy for endometrial carcinoma and was subsequently diagnosed with peritoneal angiosarcoma. Due to extensive disease, surgery was not a viable option. She was started on palliative chemotherapy, but despite treatment, her condition deteriorated further and she eventually passed away. We highlight the diagnostic challenges and considerations in these patients as well as current treatment and management options available.
Keyphrases
- rare case
- end stage renal disease
- soft tissue
- systematic review
- newly diagnosed
- locally advanced
- minimally invasive
- case report
- ejection fraction
- chronic kidney disease
- squamous cell carcinoma
- radiation induced
- palliative care
- patient reported outcomes
- peritoneal dialysis
- combination therapy
- coronary artery disease