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The IL-6/STAT Signaling Pathway and PPARα Are Involved in Mediating the Dose-Dependent Cardioprotective Effects of Fenofibrate in 5-Fluorouracil-Induced Cardiotoxicity.

Marwa Monier Mahmoud RefaieSayed ShehataAsmaa M A BayoumiNashwa Fathy Gamal El-TahawyWalaa Yehia Abdelzaher
Published in: Cardiovascular drugs and therapy (2021)
FEN demonstrated a significant cardioprotective effect against 5FU-induced cardiac damage.
Keyphrases
  • signaling pathway
  • high glucose
  • diabetic rats
  • left ventricular
  • endothelial cells
  • insulin resistance
  • adipose tissue
  • stress induced