Population Pharmacokinetics of Brigatinib in Healthy Volunteers and Patients With Cancer.
Neeraj GuptaXiaohui WangElliot OffmanMarita ProhnNarayana NarasimhanDavid KersteinMichael J HanleyKarthik VenkatakrishnanPublished in: Clinical pharmacokinetics (2021)
Results from these population pharmacokinetic analyses informed the prescribing guidance for patients with mild or moderate renal impairment in the US Prescribing Information and the European Summary of Product Characteristics for brigatinib.