Oral propranolol in prevention of severe retinopathy of prematurity: a systematic review and meta-analysis.

Amelie StritzkeN KabraS KaurH L RobertsonA Lodha

Published in: Journal of perinatology : official journal of the California Perinatal Association (2019)

Systematic assessment of studies showed that prophylactic oral propranolol appeared to be effective in preventing severe ROP in premature infants ≤32 weeks gestational age. Additional well powered, multinational, randomized control trials reporting on long-term outcomes are needed.

Keyphrases

gestational age
birth weight
preterm birth
early onset
open label
double blind
phase iii
placebo controlled
drug induced
emergency department
clinical trial
randomized controlled trial
adverse drug
physical activity
body mass index