Effects of rivaroxaban on myocardial mitophagy in the rat heart.

Tugra Gencpinar Çağatay Bilen Baris Kemahli Kivanc Kacar Pinar Akokay Serdar Bayrak Cenk Erdal

Published in: Turk gogus kalp damar cerrahisi dergisi (2023)

The present study provides an evidence that the mitophagy response is less in rivaroxaban-treated rats, showing the protective effect of rivaroxaban against acute ischemia. Rivaroxaban-treated rats may have reduced cell death in cardiomyocytes during myocardial infarction and thus have reduced damage to the heart tissue caused by myocardial infarction.

Keyphrases

atrial fibrillation
venous thromboembolism
heart failure
pulmonary embolism
cell death
left ventricular
oxidative stress
liver failure
newly diagnosed
drug induced
extracorporeal membrane oxygenation
cell cycle arrest