Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.

Roland SchmitzGeorge W WrightDa Wei HuangCalvin A JohnsonJames D PhelanJames Q WangSandrine RoullandMonica KasbekarRyan M YoungArthur L ShafferDaniel James HodsonWenming XiaoXin YuYandan YangHong ZhaoWeihong XuXuelu LiuBin ZhouWei DuWing C ChanElaine S JaffeRandy D GascoyneJoseph M ConnorsElias CampoArmando Lopez-GuillermoAndreas RosenwaldGerman OttJan DelabieLisa M RimszaKevin Tay Kuang WeiAndrew D ZelenetzJohn P LeonardNancy L BartlettBao TranJyoti ShettyYongmei ZhaoDan R SoppetStefania PittalugaWyndham H WilsonLouis M Staudt

Published in: The New England journal of medicine (2018)

We uncovered genetic subtypes of DLBCL with distinct genotypic, epigenetic, and clinical characteristics, providing a potential nosology for precision-medicine strategies in DLBCL. (Funded by the Intramural Research Program of the National Institutes of Health and others.).

Keyphrases

diffuse large b cell lymphoma
quality improvement
epstein barr virus
public health
healthcare
dna methylation
human health
genome wide
gene expression
mental health
health information
copy number
risk assessment