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Treatment with paraquat affects the expression of ferroptosis-related genes.

Xiaogang GeQiqi CaiSheng ZhangXianlong WuPan YingJingjing KeZhihui Yang
Published in: Human & experimental toxicology (2023)
ER stress and ferroptosis are critical for PQ-induced cell damage. CHAC1, ATF3, TFRC, and SLC7A11 are essential molecules implicated in PQ-induced ferroptosis that may serve as therapeutic targets for the amelioration of PQ poisoning.
Keyphrases
  • cell death
  • high glucose
  • diabetic rats
  • oxidative stress
  • drug induced
  • single cell
  • bone marrow
  • stem cells
  • transcription factor
  • endoplasmic reticulum stress
  • combination therapy
  • endothelial cells