Total flavonoids of Astragalus protects glomerular filtration barrier in diabetic kidney disease.

Pei-Yu LiuKin-Fong HongYa-Di LiuZhong-Yan SunTing-Ting ZhaoXu-Ling LiChi-Chou LaoShu-Feng TanHai-Ying ZhangYong-Hua ZhaoYing XieYou-Hua Xu

Published in: Chinese medicine (2024)

Our findings demonstrated that TFA can ameliorates the progression of DKD by ameliorating renal fibrosis and preserving the integrity of the kidney filtration barrier. These results provide pharmacological evidence supporting the use of TFA in the treatment of kidney diseases.

Keyphrases

type diabetes
mouse model
wound healing
diabetic nephropathy
endothelial cells