[Change of phenotypic properties of escape mutants and readaptants of influenza virus A (H1N1)pdm09 under the influence of selected mutations in the molecule of hemagglutinin.]
T A TimofeevaI A RudnevaA A ShilovM A BalanovaE K ArtemovVladimir T Valuev-EllistonOlga V MasalovaRegina R KlimovaTatiana Vladimirovna GrebennikovaN V КаverinPublished in: Voprosy virusologii (2020)
A comparative study of the antigenic specificity and receptor-binding activity of the escape mutants was conducted for the hemagglutinin of the influenza virus A/Moscow/01/2009 (H1N1)swl, and the readapted variants obtained for one of the escape mutants with reduced virulence for mouse. Monitoring the pleiotropic effect of mutations in the hemagglutinin H1 molecule is necessary to predict variants of the virus with pandemic potential.