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Characterisation of a musculoskeletal syndrome of enthesitis and arthritis in patients with Atopic Dermatitis treated with Dupilumab, an IL-4/13 inhibitor.

Catherine D HughesJoseph NathanLibin MathewAndrew E PinkRichard T WoolfCatherine SmithBina MenonBruce Kirkham
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
We report a new MSK syndrome of inflammatory enthesitis/arthritis/tenosynovitis in some patients receiving the IL-4 Receptor antagonist, dupilumab. This response to a cytokine-targeted therapy provides key insights into the pathogenesis of enthesitis. This article is protected by copyright. All rights reserved.
Keyphrases
  • atopic dermatitis
  • juvenile idiopathic arthritis
  • rheumatoid arthritis
  • case report
  • oxidative stress
  • systemic lupus erythematosus
  • disease activity