Identification of eQTLs using different sets of single nucleotide polymorphisms associated with carcass and body composition traits in pigs.
Felipe André Oliveira FreitasLuiz F BritoSimara Larissa FanalliJanaína Lustosa GonçalesBruna Pereira Martins da SilvaMariah Castro DurvalFernanda Nery CiconelloCamila Sabino de OliveiraLucas Echevarria NascimentoIzally Carvalho GervásioJulia Dezen GomesGabriel Costa Monteiro MoreiraBárbara Silva-VignatoLuiz Lehmann CoutinhoVivian Vezzoni de AlmeidaAline Silva Mello CesarPublished in: BMC genomics (2024)
After LD pruning, the set of SNPs identified based on the transcriptome of the skeletal muscle tissue of pigs resulted in the highest number of genes modulated by eQTLs. Most eQTLs are of the trans type and are associated with genes influencing complex traits in pigs, such as transcription factors and enhancers. Furthermore, the incorporation of SNPs from other genomic regions to the set of SNPs identified in the porcine skeletal muscle transcriptome contributed to the identification of eQTLs that had not been identified based on the porcine skeletal muscle transcriptome alone.