Differential expression of mast cells in the small airways and alveolar septa of current smokers and patients with small airway disease and COPD.
Mathew Suji EapenWenying LuSurajit DeyCollin ChiaAshutosh HardikarM D Imtaiyaz HassanPrem BhattaraiArchana Vijay GaikwadShatarupa DasPhilip M HansbroGurpreet Kaur SingheraTillie-Louise HackettSukhwinder Singh SohalPublished in: ERJ open research (2024)
This study is the first to assess the differential pattern of MC, degranulating MC and non-MC populations in the small airways and alveoli of COPD patients. The spatial positioning of the MCs within the airways showed variable correlations with lung function.